SML2637
NPD8733
≥98% (HPLC)
Synonym(s):
N-[2-(4-Methoxybenzoyl)-3-benzofuranyl]acetamide
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About This Item
Empirical Formula (Hill Notation):
C18H15NO4
CAS Number:
Molecular Weight:
309.32
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 binds to valosin-containing protein (VCP)/p97.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Kruthi Suvarna et al.
The Journal of biological chemistry, 294(9), 2988-2996 (2019-01-06)
Carcinoma-associated fibroblasts are fibroblasts activated by surrounding cancer cells. Carcinoma-associated fibroblasts exhibit enhanced cell migration, which plays an important role in cancer metastasis. Previously, we demonstrated enhanced migration of NIH3T3 fibroblasts when they were cultured in the presence of MCF7
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