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SML1019

Sigma-Aldrich

Lofexidine hydrochloride

≥98% (HPLC)

Synonym(s):

2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride, Baq 168, Britlofex, Lofetensin, Loxacor, MDL 14042

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10 MG
R 1 417,08
50 MG
R 5 363,54

R 1 417,08

List PriceR 1 446,00
Please contact Customer Service for Availability
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10 MG
R 1 417,08
50 MG
R 5 363,54

About This Item

Empirical Formula (Hill Notation):
C11H12Cl2N2O · HCl
CAS Number:
21498-08-8
Molecular Weight:
295.59
UNSPSC Code:
12352200
NACRES:
NA.77

R 1 417,08

List PriceR 1 446,00
Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C11H12Cl2N2O.ClH/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13;/h2-4,7H,5-6H2,1H3,(H,14,15);1H

InChI key

DWWHMKBNNNZGHF-UHFFFAOYSA-N

Biochem/physiol Actions

Lofexidine, a derivative of clonidine, is a very potent agonist of α2 adrenoceptors. Lofexidine is used as a treatment for withdrawl from heroin and other opiates, and as a short-activg anti-hypertensive agent.
Lofexidine, a derivative of clonidine, is a very potent agonist of a2 adrenoceptors.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000147450
0000145100
0000145100

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Questions

  1. NEED ADDITIONAL DATA FOR LOFEXIDINE HYDROCHLORIDE CAT# SML1019 SUCH AS NMR TESTING AND ANY ADDITIONAL TESTING OTHER THAN COA.

    1 answer

    1. The only in-house release testing criteria & specifications are the ones listed on the corresponding Certificate of Analysis.

      Additional testing criteria may be possible on a "CUSTOM" basis for a “BULK” quantity, if such CUSTOM testing/specification(s) is/are deemed feasible by our Team. To further discuss, kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquires" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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