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Key Documents

SML0699

Sigma-Aldrich

4′-Methoxyflavone

≥97% (HPLC)

Synonym(s):

2-(4-Methoxyphenyl)-4H-chromen-4-one, 2-(4-Methoxyphenyl)chromone

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50 MG
R 4 312,00

R 4 312,00

List PriceR 4 400,00
Please contact Customer Service for Availability
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50 MG
R 4 312,00

About This Item

Empirical Formula (Hill Notation):
C16H12O3
CAS Number:
4143-74-2
Molecular Weight:
252.26
EC Number:
223-968-8
UNSPSC Code:
12352200
NACRES:
NA.77

R 4 312,00

List PriceR 4 400,00
Please contact Customer Service for Availability

Assay

≥97% (HPLC)

form

lyophilized powder

storage condition

protect from light

color

white

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[o]1c2c([c](cc1c3ccc(cc3)OC)=O)cccc2

InChI

1S/C16H12O3/c1-18-12-8-6-11(7-9-12)16-10-14(17)13-4-2-3-5-15(13)19-16/h2-10H,1H3

InChI key

OMICQBVLCVRFGN-UHFFFAOYSA-N

Biochem/physiol Actions

4-methoxyflavone is a neuroprotective agent that inhibits the accumulation of poly (ADP-ribose) and neuronal cell death following chemically-induced DNA damage or NMDA excitation.
4-methoxyflavone is a neuroprotective agent that is an inhibitor of PARP-1 mediated cell death (parthanatos).

Other Notes

Light sensitive.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000247050
0000179548
063M4757V

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R N Gacche et al.
Archives of biochemistry and biophysics, 577-578, 35-48 (2015-05-06)
Relationship between structural diversity and biological activities of flavonoids has remained an important discourse in the mainstream of flavonoid research. In the current study anti-angiogenic, cytotoxic, antioxidant and cyclooxygenase (COX) inhibitory activities of diverse class of flavonoids including hydroxyl and

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