SMB00806

7-Ketodeoxycholic acid

≥95% (HPLC)

• Synonym(s): 3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid, 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid
• Empirical Formula (Hill Notation): C₂₄H₃₈O₅
• CAS Number: 911-40-0
• Molecular Weight: 406.56
• UNSPSC Code: 41141802
• NACRES: NA.28

Properties

• Assay: ≥95% (HPLC)
• form: powder
• packaging: pkg of 1 g; pkg of 50 mg
• color: off-white to beige
• mp: 193—198 °C
• functional group: carboxylic acid; ketone
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O[C@@H]1[C@]2([C@H]([C@H]3[C@@H]([C@@]4([C@@H](C[C@@H](CC4)O)CC3=O)C)C1)CC[C@@H]2[C@@H](CCC(=O)O)C)C
• InChI: 1S/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,20,22,25,27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,20+,22+,23+,24-/m1/s1
• InChI key: RHCPKKNRWFXMAT-RRWYKFPJSA-N

Description

General description

7-Ketodeoxycholic acid, categorized as a oxo-5beta-cholanic acid, is a bile acid derivative and a metabolite resulting from the degradation of the primary bile acid, cholic acid, by intestinal bacteria. Bile acids, natural steroid amphipathic compounds formed through cholesterol oxidation in the liver, play a crucial role in regulating lipid metabolism. They facilitate the digestion, absorption, and transport of lipids, lipid-soluble vitamins, and related molecules in the gastrointestinal tract. These bile acids also impact various aspects of cholesterol, glucose, and energy balance. However, in specific liver conditions such as intrahepatic cholestasis characterized by reduced bile flow, the accumulation of bile acids at elevated concentrations can lead to severe toxic effects. This makes 7-Ketodeoxycholic acid a compound of interest for biochemical and metabolomics research.

Application

7-Ketodeoxycholic acid finds application in metabolomics, biochemical and microbiome research.

Features and Benefits

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Other Notes

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable