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SMB00175

Sigma-Aldrich

Aromadendrin

≥95% (LC/MS-ELSD)

Synonym(s):

Dihydrokaempferol, Katuranin

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About This Item

Empirical Formula (Hill Notation):
C15H12O6
CAS Number:
480-20-6
Molecular Weight:
288.25
MDL number:
MFCD00189454
UNSPSC Code:
12352200
PubChem Substance ID:
329824841

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

InChI

1S/C15H12O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,14-18,20H/t14-,15+/m0/s1

InChI key

PADQINQHPQKXNL-LSDHHAIUSA-N

General description

Natural product derived from plant source.

Biochem/physiol Actions

Aromadendrin has been considered for potential use in the management of Type 2 diabetes due to its ability to stimulate glucose uptake and improve insulin resistance by inducing adipogenesis through increased PPAR2 expression.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wei Yun Zhang et al.
Pharmacology, 88(5-6), 266-274 (2011-11-08)
Agents that stimulate glucose uptake and improve insulin resistance may be useful in the management of type 2 diabetes mellitus (DM). Thus, the aims of this study were to assess the effects of aromadendrin, a flavonoid from Gleditsia sinensis Lam.
Ken-ichi Morimura et al.
Phytochemistry, 67(24), 2681-2685 (2006-09-16)
From the leaves of Helicia cochinchinensis, collected on Okinawa Island, seven phenolic glucosides and two terpenic glucosides were isolated. Five of the phenolic glucosides were previously known, being identified with p-coumaric and ferulic acids glucosyl esters, rhodioloside, helicidiol, and naringenin
Izabela Redzynia et al.
Molecules (Basel, Switzerland), 14(10), 4147-4158 (2009-11-20)
X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the Dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol
Ilef Limem-Ben Amor et al.
Natural product communications, 5(5), 777-782 (2010-06-05)
Flavonoid hydroxylation is one way to increase the biological activities of these molecules and the number of hydroxyl groups needed for polymerization, esterification, alkylation, glycosylation and acylation reactions. These reactions have been suggested as a promising route to enhance flavonoid
Sailesh Malla et al.
Applied and environmental microbiology, 78(3), 684-694 (2011-11-22)
7-O-Methyl aromadendrin (7-OMA) is an aglycone moiety of one of the important flavonoid-glycosides found in several plants, such as Populus alba and Eucalyptus maculata, with various medicinal applications. To produce such valuable natural flavonoids in large quantity, an Escherichia coli
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