Anti-APLP2 Antibody detects endogenous levels of total APLP2 protein.
APLP2 (amyloid precursor-like protein 2) belongs to the amyloid precursor protein family. It is mapped to human chromosome 11q24.
Immunogen
The antiserum was produced against synthesized peptide derived from human APLP2.
Immunogen Range: 241-290
Biochem/physiol Actions
Amyloid precursor-like protein 2 (APLP2) aids in the proliferation of pancreatic cancer growth and metastasis. It controls the expression of cell surface proteins. APLP2 plays an important role in chromosome replication and segregation.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Amyloid precursor-like protein 2 (APLP2) is aberrantly expressed in pancreatic cancer. Here we showed that APLP2 is increased in pancreatic cancer metastases, particularly in metastatic lesions found in the diaphragm and intestine. Examination of matched human primary tumor-liver metastasis pairs
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