S1250

(−)-α-Santonin

≥99%

• Synonym(s): (3S,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)dione, Semenen
• Empirical Formula (Hill Notation): C₁₅H₁₈O₃
• CAS Number: 481-06-1
• Molecular Weight: 246.30
• Beilstein: 89489
• EC Number: 207-560-7
• MDL number: MFCD00135865
• UNSPSC Code: 12352204
• PubChem Substance ID: 24899466
• NACRES: NA.83

Properties

• Assay: ≥99%
• mp: 172-173 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)C(C)=C3[C@H]2OC1=O
• InChI: 1S/C15H18O3/c1-8-10-4-6-15(3)7-5-11(16)9(2)12(15)13(10)18-14(8)17/h5,7-8,10,13H,4,6H2,1-3H3/t8-,10-,13-,15-/m0/s1
• InChI key: XJHDMGJURBVLLE-BOCCBSBMSA-N

Description

General description

(−)-α-Santonin is a sesquiterpene lactone. It is found in the genus Artemisia.[1]

Application

(−)-α-Santonin has been used as a eudesmane-type sesquiterpene to study its effects on impairment of 231MFP breast cancer cell survival.[2]

Biochem/physiol Actions

(−)-α-Santonin exhibits anti-helminthic properteis.[1] It exhibits therapeutic effects against intestinal round worms.[3]

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331
• Precautionary Statements: P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves