Skip to Content
Merck
All Photos(1)

Documents

PLA0214

Sigma-Aldrich

Rabbit anti-NF-kappaB1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

CVID12, DNA-binding factor KBF1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NF-kappabeta, NFKB-p105, NFKB-p50, NFkappaB, nuclear factor NF-kappa-B p50 subunit, nuclear factor kappa-B DNA binding subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, p50

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-10 μg/mg

accession no.

AAF35232.1

shipped in

wet ice

storage temp.

2-8°C

Gene Information

Immunogen

The epitope recognized by PLA0214 maps to a region between residue 1 and 50 of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) using the numbering given in entry AAF35232.1 (GeneID 4790).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

The NFKB1 gene encodes a 105 kDa protein that can undergo co-translational processing to also yield a 50 kDa protein. The 50 kDa protein is also known as NF-kappa B1/p50 and is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The 105 kDa product is also known as p105 or I kappa B gamma. p105/I kappa B gamma has been shown to function as an inhibitor protein that interacts with NF-kappa B and inhibit its DNA binding activity. p105/I kappa B gamma is a member of the I kappa B family of proteins which includes I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa B1/p105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. The classical description of the NF-kappa B transcription factor is a transcription factor that reprograms gene expression of the immune system in response to injury, infection, and stress.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service