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Key Documents

I6005

Sigma-Aldrich

myo-Inositol hexasulfate hexapotassium salt

Synonym(s):

Inositol hexakissulfate, InsS6

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About This Item

Linear Formula:
C6H6O24S6K6
CAS Number:
Molecular Weight:
889.08
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
Pricing and availability is not currently available.

storage temp.

−20°C

SMILES string

[K].OS(=O)(=O)OC1C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C1OS(O)(=O)=O

InChI

1S/C6H12O24S6.K.H/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;/h1-6H,(H,7,8,9)(H,10,11,12)(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24);;

InChI key

JYVHCOUFXHFSLT-UHFFFAOYSA-N

Biochem/physiol Actions

InsS6 has a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. It is used as a control in studies of the cellular actions of phytic acid. It is also a competitive inhibitor of Aspergillus phytase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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G Oshima
Thrombosis research, 58(3), 243-250 (1990-05-01)
Thrombin-clotting time of fibrinogen was delayed by inositol hexasulfate (IHS). Clotting time of the recalcified plasma was also delayed by IHS. Moreover, when IHS was intravenously injected into anesthetized male rabbits (0.11 mmoles/kg), it delayed clotting time of the recalcified
R Kojima et al.
Japanese journal of pharmacology, 53(3), 347-358 (1990-07-01)
We examined the protective effect of inositol hexasulfate (IS6) against tobramycin (TOB)-induced nephrotoxicity. In the electrophoretic analysis, TOB alone and IS6 alone were observed as single spots on the cathode and anode sides, respectively. However, in the mixture of TOB
N M Dean et al.
The Biochemical journal, 250(2), 493-500 (1988-03-01)
Previous studies demonstrated a multiplicity of isomers of inositol phosphates in GH3 rat pituitary tumour cells. In order to determine their origin, we have investigated the metabolism of radiolabelled inositol phosphates (IPn) in GH3 cell homogenates by using h.p.l.c. I(1,4,5)P3
Abul H J Ullah et al.
Biochemical and biophysical research communications, 306(2), 603-609 (2003-06-14)
Fungal phyA gene from Aspergillus ficuum (niger) was cloned and expressed in potato leaves. The recombinant enzyme was stable and catalytically active. The expressed protein in the leaves of the dicotyledonous plant retained most physical and catalytic properties of the
S Vemuri et al.
The Journal of pharmacy and pharmacology, 46(6), 481-486 (1994-06-01)
The influence of sulphated ligand and pH on thermal denaturation of basic fibroblast growth factor (bFGF) was investigated by differential scanning calorimetry (DSC), and verified by fluorescence spectrophotometry. Purity of bFGF before and after heat denaturation was assessed by SDS-PAGE

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