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GW22383A

Sigma-Aldrich

Anti-PNLIPRP2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203

biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, rat, mouse

manufacturer/tradename

Genway 15-288-22383A

technique(s)

western blot: suitable

NCBI accession no.

NP_005387.1

UniProt accession no.

P54317

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PNLIPRP2(5408)

Immunogen

Immunogen Sequence: GI # 4885555, sequence 16-139
Recombinant pancreatic lipase-related protein 2

Application

Anti-PNLIPRP2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

PNLIPRP2 (pancreatic lipase-related protein 2) is also know as PLRP2 . It can digest fats in human milk and formula. In mice, it is essential for fat digestion, and in humans, its role in fat digestion is unclear. IL-4 induces PLRP2 in cytotoxic T lymphocytes (CTLs). PLRP2 can help in killing tumor cells and is alone required for lipid-dependent cytotoxicity mediated by cytotoxic T lymphocytes (CTLs).

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Karin Johnson et al.
Pediatric research, 74(2), 127-132 (2013-06-05)
Dietary fats must be digested into fatty acids and monoacylglycerols prior to absorption. In adults, colipase-dependent pancreatic triglyceride lipase (PTL) contributes significantly to fat digestion. In newborn rodents and humans, the pancreas expresses low levels of PTL. In rodents, a
Bryce N Alves et al.
Cell biochemistry and function, 27(5), 296-308 (2009-06-24)
IL-4 induces a lipase, pancreatic lipase related protein 2 (PLRP2), in cytotoxic T lymphocytes (CTLs). Because PLRP2 in semen can mediate lipid-dependent toxicity to sperm, we questioned whether CTL-derived PLRP2 could support similar cytotoxicity toward tumor cells. Recombinant PLRP2 was
Xunjun Xiao et al.
The Journal of biological chemistry, 286(30), 26353-26363 (2011-06-10)
In newborn mice, PLRP2 is essential for fat digestion. In human infants, the role of PLRP2 in fat digestion is unclear, as it has poor activity against long-chain triglycerides in vitro. Also, many infants carry a genetic polymorphism resulting in

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