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D3875

Sigma-Aldrich

Sodium dehydrocholate

~95%

Synonym(s):

3,7,12-Trioxo-5β-cholanic acid sodium salt, Dehydrocholic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C24H33NaO5
CAS Number:
145-41-5
Molecular Weight:
424.51
Beilstein:
4119624
EC Number:
205-652-1
MDL number:
MFCD00066411
UNSPSC Code:
12000000

description

anionic

Assay

~95%

SMILES string

[Na+].[H][C@@]12CC(=O)CC[C@]1(C)[C@@]3([H])CC(=O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])C(=O)C2)[C@H](C)CCC([O-])=O

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M K Mohanty et al.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 31(3), 184-189 (2011-05-13)
Small ductules communicating with the bile ducts have been described at the porta hepatis in extrahepatic biliary atresia (EHBA) and these form the basis for hepatic portoenterostomy. The use of cholagogues like dehydrocholic acid (DHC) and ursodeoxycholic acid (UDCA) to
Ana I Prieto et al.
Journal of bacteriology, 191(11), 3615-3622 (2009-04-07)
A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA gene. Disruption of asmA suppressed bile sensitivity also in
Yuji Sakai et al.
Hepato-gastroenterology, 55(86-87), 1801-1805 (2008-12-24)
The aim of this study was to investigate whether exogenous dehydrocholic acid (DHCA) was useful to enhance the delineation of hepatolithiasis. Our study population comprised 9 patients. Magnetic resonance cholangiopancreatography (MRCP) was acquired before and after the administration of DHCA.
Ernst Seiffert et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(36), 7829-7836 (2004-09-10)
Perturbations in the integrity of the blood-brain barrier have been reported in both humans and animals under numerous pathological conditions. Although the blood-brain barrier prevents the penetration of many blood constituents into the brain extracellular space, the effect of such
Tao Huang et al.
Biotechnology and applied biochemistry, 42(Pt 1), 47-56 (2004-12-23)
A novel chemically modified insulin, -NB29-DHC-insulin (where DHC-insulin stands for dehydrocholyl-insulin), was prepared by covalent linkage of DHC (dehydrocholic acid) to the -amino group of LysB29 without any protecting agent and analysed by PAGE and reversed-phase HPLC. DHC-insulin was identified
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