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Key Documents

C5374

Sigma-Aldrich

CB-DMB

≥98% (HPLC)

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5 MG
R 5 278,28
25 MG
R 14 213,92

R 5 278,28

List PriceR 5 386,00

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5 MG
R 5 278,28
25 MG
R 14 213,92

About This Item

Empirical Formula (Hill Notation):
C22H23Cl2N7O
CAS Number:
Molecular Weight:
472.37
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

R 5 278,28

List PriceR 5 386,00

Please contact Customer Service for Availability

Request a Bulk Order

Quality Level

Assay

≥98% (HPLC)

form

solid

solubility

DMSO: 20 mg/mL

storage temp.

2-8°C

SMILES string

Cc1ccc(CNC(=N)NC(=O)c2nc(Cl)c(NCc3ccc(Cl)cc3)nc2N)c(C)c1

InChI

1S/C22H23Cl2N7O/c1-12-3-6-15(13(2)9-12)11-28-22(26)31-21(32)17-19(25)30-20(18(24)29-17)27-10-14-4-7-16(23)8-5-14/h3-9H,10-11H2,1-2H3,(H3,25,27,30)(H3,26,28,31,32)

InChI key

MGLQFHOCPGELNL-UHFFFAOYSA-N

Biochem/physiol Actions

CB-DMB is a specific and potent inhibitor of the Na+-Ca2+exchanger (NCX).
CB-DMB is a specific and potent inhibitor of the Na+-Ca2+exchanger (NCX); pan-inhibitor of the NA+-Ca2+exchanger isoforms.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.

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