B8061

N-Butyl-N-(4-hydroxybutyl)nitrosamine

ISOPAC^®, ≥90% (GC)

• Synonym(s): BBN, N-Butyl-N-butan-4-ol-nitrosamine, N-Butyl-N-nitroso-4-aminobutanol, OH-BBN
• Empirical Formula (Hill Notation): C₈H₁₈N₂O₂
• CAS Number: 3817-11-6
• Molecular Weight: 174.24
• UNSPSC Code: 12352116
• NACRES: NA.25

Properties

• Assay: ≥90% (GC)
• form: liquid
• storage temp.: 2-8°C
• InChI: 1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3
• InChI key: DIKPQFXYECAYPC-UHFFFAOYSA-N

Description

Application

N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.

Biochem/physiol Actions

Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.

Packaging

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Caution

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H350
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 296.6 °F
• Flash Point(C): 147 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves