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A6883

Sigma-Aldrich

Atropine methyl bromide

≥99% (TLC), powder

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About This Item

Empirical Formula (Hill Notation):
C18H26NO3 · Br
CAS Number:
2870-71-5
Molecular Weight:
384.31
EC Number:
220-700-1
MDL number:
MFCD00050293
UNSPSC Code:
12352200
PubChem Substance ID:
329770907

Assay

≥99% (TLC)

form

powder

color

white to off-white

solubility

H2O: 50 mg/mL

SMILES string

Br.C[N]1(C)[C@@H]2CC[C@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C18H26NO3.BrH/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13;/h3-7,14-17,20H,8-12H2,1-2H3;1H/t14-,15+,16?,17?;

InChI key

YBFLMRSYEWDJEJ-ZNHDNBJUSA-N

Gene Information

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

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Biochem/physiol Actions

Competitive muscarinic acetylcholine receptor antagonist that does not cross the blood-brain barrier.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Timothy A Yap et al.
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M M Knuepfer et al.
The American journal of physiology, 276(1 Pt 2), R103-R112 (1999-01-14)
It has been suggested that toxicity to cocaine is related to the relative rate of cocaine metabolism by cholinesterases and to activation of cholinergic receptors either directly or by reflex mechanisms. We examined these possibilities by altering cholinesterase activity and
H Ohnuma et al.
Journal of the autonomic nervous system, 57(1-2), 43-48 (1996-02-05)
Hepatic glucoreceptor-vagal afferent inputs to the central nervous system and pancreatic vagal efferent stimuli are important for insulin secretion. In the present study, we examined the effect of intracerebroventricular (i.c.v.) injection of atropine methyl bromide (methylatropine) on the insulin response
G J Kirouac et al.
The American journal of physiology, 273(6 Pt 2), H2549-H2557 (1998-01-22)
Experiments were done in alpha-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect of L-glutamate (Glu) stimulation of the substantia nigra (SN) and ventral tegmental area (VTA) on arterial pressure (AP) and heart rate (HR). Glu stimulation of the
Takahiko Yoshimoto et al.
The journal of physiological sciences : JPS, 61(5), 373-383 (2011-06-30)
In this study, after confirming the suppression of autonomic nervous function by isoflurane anesthesia using autonomic antagonists, we pharmacologically investigated the involvement of vasomotor and cardiac sympathetic functions in systolic blood pressure variability (SBPV) frequency components in conscious rats at
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