A251
A-85380 dihydrochloride
solid
Synonym(s):
3-((2S)-Azetidinylmethoxy)pyridine dihydrochloride
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About This Item
Empirical Formula (Hill Notation):
C9H12N2O · 2HCl
Molecular Weight:
237.13
UNSPSC Code:
12352200
PubChem Substance ID:
form
solid
optical activity
[α]20/D −5.2°, c = 0.5 in methanol(lit.)
color
off-white
solubility
H2O: 10 mg/mL
SMILES string
Cl[H].Cl[H].C1C[C@H](COc2cccnc2)N1
Application
The 5-125I-analog has been used as a selective radioligand for the α4β2 nAChR subtype. Fluorinated analogs have been used for PET imaging of nAChRs.
Biochem/physiol Actions
Potent and selective neuronal nicotinic acetylcholine receptor (nAChR) agonist.
Caution
Hygroscopic
Legal Information
Manufactured and sold under exclusive license from Abbott Laboratories.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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