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A131

Supelco

Alprenolol hydrochloride

Synonym(s):

1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C15H23NO2 · HCl
CAS Number:
13707-88-5
Molecular Weight:
285.81
EC Number:
237-244-4
MDL number:
MFCD00069212
UNSPSC Code:
41116107

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CC(C)NCC(O)COc1ccccc1CC=C

InChI

1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H

InChI key

RRCPAXJDDNWJBI-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Noel Dew et al.
Colloids and surfaces. B, Biointerfaces, 89, 53-60 (2011-10-01)
To fully utilize the extended contact time of gel formulations a novel formulation with drug containing catanionic aggregates offering prolonged drug release and skin penetration were investigated. This study aimed to further explore the drug release process from catanionic vesicles
Harri Härmä et al.
Journal of biomolecular screening, 14(8), 936-943 (2009-08-18)
In this article, a single-label separation-free fluorescence technique is presented as a potential screening method for cell-based receptor antagonists and agonists.The time-resolved fluorescence technique, quenching resonance energy transfer (QRET), relies on a single-labeled binding partner in combination with a soluble
Naoya Kishikawa et al.
Journal of chromatography. A, 1218(20), 3002-3006 (2011-04-15)
A novel fluorescent labeling method for alprenolol was developed based on Mizoroki-Heck coupling reaction. We designed and synthesized fluorescent aryl iodide, 4-(4,5-diphenyl-1H-imidazol-2-yl)iodobenzene (DIBI) as a labeling reagent. DIBI has a lophine skeleton carrying an iodide atom acting as fluorophore and
Marjukka Ikonen et al.
Colloids and surfaces. B, Biointerfaces, 78(2), 275-282 (2010-04-20)
In this work, isothermal titration calorimetry (ITC) combined with zeta potential measurements was used to study the binding and partitioning of three beta-blockers, alprenolol, labetalol and propranolol, and the local anaesthetic tetracaine into liposomes. The thermodynamic parameters of enthalpy, entropy
Ron O Dror et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(32), 13118-13123 (2011-07-23)
How drugs bind to their receptors--from initial association, through drug entry into the binding pocket, to adoption of the final bound conformation, or "pose"--has remained unknown, even for G-protein-coupled receptor modulators, which constitute one-third of all marketed drugs. We captured
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Chromatograms

application for HPLC

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