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202-05N

Sigma-Aldrich

Human Umbilical Artery Endothelial Cells: HUAEC, neonatal

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About This Item

UNSPSC Code:
41106514
NACRES:
NA.81

biological source

human umbilicus (normal arteries)

Quality Level

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 46

morphology

Endothelial

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

arthritis; diabetes; cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

General description

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Human Umbilical Artery Endothelial Cells (HUAEC) establish a solid platform for drug discovery, and studies related to tissue regeneration and atherosclerosis. Endothelial cells play critical roles in vascular homeostasis and vessel wall tone. In addition, they participate in platelet aggregation and coagulation. HUAEC also influence lymphocyte activation and chmoattractant activity.

Cell Line Origin

Artery

Application

fluid filtration, blood vessel tone, hemostasis, neutrophil recruitment, hormone trafficking, angiogenesis, vasoconstriction, vasodilation, blood pressure control, cell proliferation, migration, endothelial cell-dependent lymphocyte activation, chemoattractant activity, coagulation activation and inhibition

Components

Basal Medium containing 10% FBS & 10% DMSO

Preparation Note

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 15 doublings

Subculture Routine

Please refer to the HUAEC Culture Protocol.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Warrick Ma et al.
ACS omega, 7(18), 15540-15546 (2022-05-17)
An alkyne-functionalized elastomer derived from sebacic acid, 1,3-propanediol, and alkyne-functionalized serinol is synthesized via melt condensation. A low-power UV lamp triggers the cross-linking rapidly via thiol-yne click chemistry. The cross-linking behavior is studied by photorheology and NMR spectroscopy. The resultant

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