American journal of respiratory and critical care medicine, 190(2), 208-217 (2014-06-18)
Pulmonary hypertension (PH) associated with fibrotic idiopathic interstitial pneumonia (IIP; idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia) confers important additional morbidity and mortality. To evaluate the safety and clinical efficacy of the dual endothelin-1 receptor antagonist bosentan in this patient
Although a number of studies have reported that cocrystals can form by heating a physical mixture of two components, details surrounding heat-induced cocrystal formation remain unclear. Here, we attempted to clarify the thermal behavior of a physical mixture and cocrystal
Proceedings of the National Academy of Sciences of the United States of America, 104(33), 13519-13524 (2007-08-09)
TRPA1 is an excitatory ion channel expressed by a subpopulation of primary afferent somatosensory neurons that contain substance P and calcitonin gene-related peptide. Environmental irritants such as mustard oil, allicin, and acrolein activate TRPA1, causing acute pain, neuropeptide release, and
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