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Merck

P3C030C01

Millipore

Pellicon® 3 Cassette with Ultracel® Membrane

filtration area 0.11 m2, NMWCO 30 kDa

Synonym(s):

Pellicon® 3 Cassette with Ultracel 30 kDa Membrane, C screen, 0.11 m2

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About This Item

UNSPSC Code:
41104903
eCl@ss:
32031602

material

TPE seal
composite regenerated cellulose (CRC)
polypropylene cap (for end)
polypropylene screen

Quality Level

feature

holdup volume 18 mL (in feed channel)

manufacturer/tradename

Pellicon®

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours)
4-6 L/min-m2 recirculation rate
40 psi max. transmembrane pressure at 4-50 °C
6.9 bar max. inlet pressure (100 psi)
80 psi max. transmembrane pressure at 4-40 °C

technique(s)

analytical sample preparation: suitable
buffer exchange: suitable
protein purification: suitable (concentration)

H

2.3 cm (0.90 in.)

L

20.6 cm (8.1 in.)

W

5.6 cm (2.2 in.)

filtration area

0.11 m2

membrane area

0.11 m2

gravimetric extractables

≤1500 mg/m2

matrix

Ultracel® (Membrane)

pore size

30 kDa NMWCO

pH

2-13

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General description

Pellicon® 3 filtration devices are advanced, high-performance cassettes ideal for today’s higher titer therapeutic antibodies as well as the more demanding filtration processes that require higher operating pressures, temperatures and caustic cleaning regimes.

The Pellicon® 3 Cassette with Ultracel® Membrane is designed for the filtration of therapeutic proteins (such as monoclonal antibodies) and recombinant and non-recombinant proteins.

This P3C030C01 Pellicon® 3 ultrafiltration device features a pore size of 30 kDa NMWCO, a filtration area of 0.11 m2, a PLCTK membrane, and dimensions measuring 0.8 cm (H) x 5.6 cm (W) x 20.6 cm (L).

Features and Benefits

  • Rugged & reliable – ideally suited for today′s more demanding filtration processes
  • High performance – produces excellent resolution, yields and back-pressure resistance
  • Optimum product recovery – thanks to proven membrane technology
  • Void-free technology – leading-edge membranes resolve virtually any separation challenge
  • Defect-free, superior adhesion – Ultracel®uses composite membranes cast on a microporous substrate
  • Automated manufacturing – delivers unbeatable performance, consistency and reliability
  • Easy installation & care – simple to install and maintain

Other Notes

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Analysis Note

Gravimetric Extractables: after 24 hours in water at controlled room temperature

Legal Information

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

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Articles

Get practical guidance on using single-pass tangential flow filtration in your downstream process and scaling between capsules and cassettes.

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

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