8.51046-M

HMPB

Novabiochem^®

• Synonym(s): HMPB, 4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid
• Empirical Formula (Hill Notation): C₁₂H₁₆O₅
• CAS Number: 136849-75-7
• Molecular Weight: 240.25
• MDL number: MFCD00153508
• UNSPSC Code: 12352005
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• Assay: ≥99% (TLC)
• form: powder
• reaction suitability: reagent type: linker
• manufacturer/tradename: Novabiochem^®
• mp: 83 °C
• application(s): peptide synthesis
• storage temp.: 2-8°C
• InChI: 1S/C12H16O5/c1-16-11-7-10(5-4-9(11)8-13)17-6-2-3-12(14)15/h4-5,7,13H,2-3,6,8H2,1H3,(H,14,15)
• InChI key: HXOYWJCDYVODON-UHFFFAOYSA-N

Description

General description

A 1% TFA-labile dialkoxybenzyl linker for the preparation of protected peptides by the Fmoc strategy [1]. This linker gives purer peptides compared to Sheppard′s original 4-hydroxymethyl-3-methoxyphenoxyacetic acid due to its increased acid sensitivity.

The product number for this product was previously 01-60-0029.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Linkage

Replaces: 01-60-0029

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(157A)): ≥ 99 %
Purity (TLC(0811)): ≥ 99 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable