8.22265

Chloroform

EMPLURA^®

• Synonym(s): TCM, Trichloromethane, Methane trichloride, Methyl trichloride, Methylidyne trichloride, Trichloromethane
• Empirical Formula (Hill Notation): CHCl₃
• CAS Number: 67-66-3
• Molecular Weight: 119.38
• Beilstein: 1731042
• MDL number: MFCD00000826
• UNSPSC Code: 12352101
• EC Index Number: 200-663-8
• NACRES: NA.21

Properties

• vapor density: 4.1 (vs air)
• Quality Level: 200
• vapor pressure: 160 mmHg ( 20 °C)
• product line: EMPLURA^®
• Assay: ≥99% (GC)
• form: liquid
• potency: 695 mg/kg LD₅₀, oral (Rat); >3980 mg/kg LD₅₀, skin (Rabbit)
• impurities: ≤0.1% Water
• evapn. residue: ≤0.0010%
• refractive index: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.492 g/mL at 25 °C (lit.)
• storage temp.: 2-25°C
• SMILES string: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

General description

EMPLURA^® is our low-cost alternative to high-purity qualities. With EMPLURA we offer a range of solvents for a plurality of basic applications in non-regulated industries and for less demanding applications, preparative laboratory work and cleaning purposes. EMPLURA solvents provide adequate specifications with the most important parameters.

Application

• Improved lipid analysis using a 2D-LC-MS system with a novel injection procedure.: This research introduces an advanced lipid analysis method that incorporates chloroform in a dual-dimensional liquid chromatography-mass spectrometry setup, enhancing lipidomic studies′ precision and throughput (Schiell et al., 2024).


• Uncovering the Power of HSCCC: Separation of Diastereomeric and Regioisomeric Styrylpyrones from the Stem Bark of Goniothalamus leiocarpus.: Describes the use of chloroform in high-speed countercurrent chromatography, which is critical for separating complex natural product mixtures (Mu et al., 2024).


• Determination of aflatoxins in rice from Penang, Malaysia by dispersive liquid-liquid micro-extraction and LC-MS/MS.: This study employs chloroform in a dispersive liquid-liquid micro-extraction technique for detecting aflatoxins in rice, highlighting its role in food safety (Ismail et al., 2024).

Analysis Note

Purity (GC): ≥ 99.0 %
Identity (IR): conforms
Density (d 20 °C/ 4 °C): 1.474 - 1.479
Evaporation residue: ≤ 0.0010 %
Water: ≤ 0.10 %
Stabilized with 0,7 - 1,0% Ethanol

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash