1.03000

Triacetin

EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP

• Synonym(s): Triacetin
• Empirical Formula (Hill Notation): C₉H₁₄O₆
• CAS Number: 102-76-1
• Molecular Weight: 218.20
• MDL number: MFCD00008716
• UNSPSC Code: 12352108
• EC Index Number: 203-051-9

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• vapor pressure: <0.1 hPa ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• form: liquid
• autoignition temp.: 430 °C
• expl. lim.: 1.1-7.7 % (v/v)
• pH: 5.0-6.0 (20 °C, 50 g/L in H₂O)
• bp: 258 °C/1013 hPa
• mp: -78 °C
• transition temp: flash point 138 °C
• solubility: 64 g/L
• density: 1.16 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; solid formulation
• storage temp.: 15-25°C
• SMILES string: O(C(COC(=O)C)COC(=O)C)C(=O)C
• InChI: 1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3
• InChI key: URAYPUMNDPQOKB-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Triacetin is used as solvent in liquid formulations and plasticizer in film coatings.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 298.4 °F - closed cup
• Flash Point(C): 148 °C - closed cup