850481C
Avanti
16:0-18:0 (9-10BR) PC
1-palmitoyl-2-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine, chloroform
Synonym(s):
1-hexadecanoyl-2-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine
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About This Item
Empirical Formula (Hill Notation):
C42H82NO8PBr2
CAS Number:
Molecular Weight:
919.88
UNSPSC Code:
12352211
NACRES:
NA.25
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Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (850481C-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850481C
concentration
10 mg/mL (850481C-10mg)
shipped in
dry ice
storage temp.
−20°C
General description
16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) is a brominated phosphatidylcholine lipid. This lipid is stable for one year.
Application
16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) has been used in large unilamellar vesicles (LUVs) and small unilamellar vesicles (SUVs) for fluorescence quenching. It has also been used to prepare large unilamellar vesicles (LUV) for liposome co-sedimentation assay. It may be used as a component in large unilamellar liposomes for parallax analysis and in lipid vesicle preparation for tryptophan (Trp) penetration depth experiments/bromine quenching experiments.
Biochem/physiol Actions
16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) can act as a deep quencher.
Packaging
5 mL Clear Glass Sealed Ampule (850481C-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system
WGK
WGK 3
Certificates of Analysis (COA)
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Caroline Montagner et al.
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During intoxication of a cell, the translocation (T) domain of the diphtheria toxin helps the passage of the catalytic domain across the membrane of the endosome into the cytoplasm. We have investigated the behavior of the N-terminal region of the
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The Journal of biological chemistry, 290(2), 744-754 (2014-11-28)
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Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed. Single-domain antibodies (VHH) have been examined as a countermeasure for BoNT because of their high stability and
John M Harrington et al.
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The bloodstream developmental forms of pathogenic African trypanosomes are uniquely susceptible to killing by small hydrophobic peptides. Trypanocidal activity is conferred by peptide hydrophobicity and charge distribution and results from increased rigidity of the plasma membrane. Structural analysis of lipid-associated
Candace M Pfefferkorn et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2821-2828 (2015-08-25)
Apolipoproteins are essential human proteins for lipid metabolism. Together with phospholipids, they constitute lipoproteins, nm to μm sized particles responsible for transporting cholesterol and triglycerides throughout the body. To investigate specific protein-lipid interactions, we produced and characterized three single-Trp containing
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