Journal of pharmaceutical sciences, 100(8), 3268-3283 (2011-04-08)
The production of salt or cocrystalline forms is a common approach to alter the physicochemical properties of pharmaceutical compounds. The goal of this work was to evaluate the impact of anion choice (succinate, adipate, and sulfate) on the physicochemical characteristics
Nature chemical biology, 8(11), 887-889 (2012-09-25)
Mutations in an enzyme can result in a neomorphic catalytic activity in cancers. We applied cancer-associated mutations from isocitrate dehydrogenases to homologous residues in the active sites of homoisocitrate dehydrogenases to derive enzymes that catalyze the conversion of 2-oxoadipate to
Biotechnology and bioengineering, 108(6), 1298-1306 (2011-02-18)
A limited life cycle assessment (LCA) was performed on a combined biological and chemical process for the production of adipic acid, which was compared to the traditional petrochemical process. The LCA comprises the biological conversion of the aromatic feedstocks benzoic
Journal of hazardous materials, 189(1-2), 158-166 (2011-03-15)
The removal of methylene blue (MB) as a cationic dye from aqueous solution by the stabilized Fe(3)O(4) nano-particles with the extracted pectin from apple waste (FN-PA) increased due to using the cross-linked forms of the bound pectin on the nano-particles
Adipic acid is a key compound in the chemical industry, where it is mainly used in the production of polymers. The conventional process of its generation requires vast amounts of energy and, moreover, produces environmentally deleterious substances. Thus, there is
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