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Key Documents

78153

Sigma-Aldrich

N-Phenylanthranilic acid

technical, ≥95% (T)

Synonym(s):

2-(Phenylamino)benzoic acid, Diphenylamine-2-carboxylic acid, DpC

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About This Item

Linear Formula:
2-(C6H5NH)C6H4CO2H
CAS Number:
Molecular Weight:
213.23
Beilstein:
1456607
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

grade

technical

Assay

≥95% (T)

form

powder

mp

182-185 °C (lit.)
182-185 °C

application(s)

peptide synthesis

SMILES string

OC(=O)c1ccccc1Nc2ccccc2

InChI

1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)

InChI key

ZWJINEZUASEZBH-UHFFFAOYSA-N

Gene Information

human ... TTR(7276)

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Walter E Finkbeiner et al.
American journal of physiology. Lung cellular and molecular physiology, 301(4), L402-L414 (2011-07-05)
We investigated how cystic fibrosis (CF) alters the relationship between Cl(-) and mucin secretion in cultures of non-CF and CF human tracheobronchial gland mucous (HTGM and CFTGM, respectively) cells. Biochemical studies showed that HTMG cells secreted typical airway mucins, and
Tarek Aboul-Fadl et al.
Molecules (Basel, Switzerland), 16(5), 3544-3551 (2011-04-30)
A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was
Graham R Betton et al.
Toxicologic pathology, 40(4), 682-694 (2012-02-04)
N-phenylanthranilic acid is a chloride channel blocker that causes renal papillary necrosis in rats. Studies were conducted in two strains of male rats to evaluate novel biomarkers of nephrotoxicity. Han-Wistar rats were given daily oral doses of 50, 350, or
Jian-Yang Du et al.
Biology of reproduction, 80(1), 13-23 (2008-09-12)
The present study investigated the effects of dopamine on chloride transport across cultured rat caudal epididymal epithelium. The results showed that dopamine induced a biphasic short-circuit current (Isc) in a concentration-dependent manner. The dopamine-induced response consisted of an initial rapid
Priyanka Garg et al.
Molecular pharmacology, 82(5), 795-802 (2012-08-02)
Niflumic acid, 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid (NFA), a nonsteroidal anti-inflammatory drug that blocks cyclooxygenase (COX), was shown previously to activate [Na(+)](i)-regulated Slo2.1 channels. In this study, we report that other fenamates, including flufenamic acid, mefenamic acid, tolfenamic acid, meclofenamic acid, and a

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