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672130

Sigma-Aldrich

O-(2-Aminoethyl)polyethylene glycol

Mp 5,000

Synonym(s):

Polyethylene glycol, Aminopolyethylene glycol 5,000

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About This Item

Linear Formula:
NH2(CH2CH2O)nH
CAS Number:
32130-27-1
MDL number:
MFCD00286223
UNSPSC Code:
51171641
PubChem Substance ID:
24885110
NACRES:
NA.22

mol wt

Mp 5,000

Ω-end

hydroxyl

α-end

amine

Application

O-(2-Aminoethyl)polyethylene glycol (PEG-NH2) can be used:
  • As a capping ligand in the synthesis of water-dispersible and non-toxic nanocrystals (ZnS:Mn) for the development of environment friendly materials.
  • In the surface modification of magnetic nanoparticles (MNPs) for a variety of biomedical applications.

Bottomless glass bottle. Contents are inside inserted fused cone.
Reactant for:
  • Preparation of pH responsive self-healing hydrogels formed by boronate-catechol complexation
  • Preparation of core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP
  • Preparation of drug-loaded bivalent-bottle-brush polymers by graft-through ROMP

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Syntheses of Biologically Non-Toxic ZnS: Mn Nanocrystals by Surface Capping with O-(2-aminoethyl) polyethylene Glycol and O-(2-carboxyethyl) polyethylene Glycol Molecules
Kong H-Y, et al.
Bull. Korean Chem. Soc., 34(4), 1181-1187 (2013)
Potential of magnetic nanoparticles for targeted drug delivery
Yang H-W, et al.
Nanotechnology, Science and Applications, 5(4), 73-73 (2012)

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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