542393

4-Methyl-3-thienylboronic acid

≥95%

• Synonym(s): (4-Methylthien-3-yl)boronic acid, (4-Methylthiophen-3-yl)boronic acid, (4-Methylthiophen-3-yl)dihydroxyborane, 4-Methyl-3-thiopheneboronic acid
• Empirical Formula (Hill Notation): C₅H₇BO₂S
• CAS Number: 177735-11-4
• Molecular Weight: 141.98
• MDL number: MFCD04039882
• UNSPSC Code: 12352103
• PubChem Substance ID: 24878602

Properties

• Assay: ≥95%
• mp: 138-144 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: Cc1cscc1B(O)O
• InChI: 1S/C5H7BO2S/c1-4-2-9-3-5(4)6(7)8/h2-3,7-8H,1H3
• InChI key: LVPFZXKLROORIK-UHFFFAOYSA-N

Description

Application

Reactant for preparation of biologically active molecules:

• Selective sphingosine phosphate receptor antagonists
• Biarylimidazole derivatives as H⁺/K⁺ ATPase inhibitors
• Benzothienopyrimidinones as inhibitors of human protooncogene proviral insertion site in moloney murine leukemia virus kinases

Used in:

• Synthesis of arene-functionalized fullerenes via rhodium-catalyzed hydroarylation
• Suzuki cross-coupling reactions

Analysis Note

May contain up to 1 equivalent of water

Other Notes

Contains varying amounts of anhydride.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves