Sodium pyruvate-3-13C is an isotopic analogue of sodium pyruvate.
Application
Sodium pyruvate-3-13C is used to study the brain metabolism of exogenous pyruvate.It is also used to investigate the pyruvate metabolism in living cancer cells.
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Journal of neurochemistry, 95(1), 284-293 (2005-09-27)
Pyruvate given in large doses may be neuroprotective in stroke, but it is not known to what degree the brain metabolizes pyruvate. Intravenous injection of [3-13C]pyruvate led to dose-dependent labelling of cerebral metabolites so that at 5 min after injection
The Journal of biological chemistry, 289(9), 6212-6224 (2014-01-15)
Metabolic reprogramming facilitates cancer cell growth, so quantitative metabolic flux measurements could produce useful biomarkers. However, current methods to analyze flux in vivo provide either a steady-state overview of relative activities (infusion of (13)C and analysis of extracted metabolites) or
Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.
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