Skip to Content
Merck
All Photos(1)

Documents

167177

Sigma-Aldrich

5-Hydroxy-2(3H)-benzofuranone

97%

Synonym(s):

2,5-Dihydroxyphenylacetic acid lactone, Homogentisic lactone

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H6O3
CAS Number:
2688-48-4
Molecular Weight:
150.13
Beilstein:
128621
EC Number:
220-252-7
MDL number:
MFCD00005857
UNSPSC Code:
12352100
PubChem Substance ID:
24850197
NACRES:
NA.22

Assay

97%

form

powder

mp

192-194 °C (lit.)

SMILES string

Oc1ccc2OC(=O)Cc2c1

InChI

1S/C8H6O3/c9-6-1-2-7-5(3-6)4-8(10)11-7/h1-3,9H,4H2

InChI key

POUITAHNNRJWMA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

5-Hydroxy-2(3H)-benzofuranone participates in lewis acid mediated synthesis of 2(3H)-benzofuranones.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lewis acid promoted synthesis of 2 (3H)-benzofuranones.
Babu BR, et al.
Indian J. Chem. B, 45(11), 2546-2546 (2006)
Hagai Tavori et al.
Bioorganic & medicinal chemistry, 16(15), 7504-7509 (2008-06-24)
Paraoxonase1 (PON1) is a HDL bound enzyme and many of the anti-atherogenic properties of HDL are attributed to PON1. The enzyme precise mechanism of protective action and its endogenous substrate remain elusive. PON1 hydrolyzes organophosphates, arylesters and lactones, whereas the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service