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Sigma-Aldrich

Triethylenetetramine tetrahydrochloride

97%

Synonym(s):

Cuprior, Trientine tetrahydrochloride

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About This Item

Linear Formula:
NH2CH2CH2(NHCH2CH2)2NH2 · 4HCl
CAS Number:
4961-40-4
Molecular Weight:
292.08
EC Number:
225-604-3
MDL number:
MFCD00012890
UNSPSC Code:
12352100
PubChem Substance ID:
24849963
NACRES:
NA.22

Assay

97%

mp

269-270 °C (lit.)

SMILES string

Cl.Cl.Cl.Cl.NCCNCCNCCN

InChI

1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H

InChI key

OKHMDSCYUWAQPT-UHFFFAOYSA-N

Related Categories

General description

Triethylenetetramine tetrahydrochloride is a copper-chelating agent

Application

Triethylenetetramine tetrahydrochloride was used as primary amine displacer in affinity chromatography.

Biochem/physiol Actions

Triethylenetetramine tetrahydrochloride induces apoptosis of acinar cells of the pancreas in male Fischer 344 rats.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Structural characteristics of low-molecular-mass displacers for cation-exchange chromatography: II. Role of the stationary phase.
Shukla AA, et al.
Journal of Chromatography A, 872(2), 295-310 (1998)
S Kishimoto et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 45(8), 489-495 (1994-04-01)
Male Fischer 344 rats weighing 80-90 g were fed on a copper-depleted diet supplemented with 0.6% triethylenetetramine tetrahydrochloride (a copper chelator), and the death of pancreatic acinar cells of these rats was investigated morphologically and biochemically. The weight of the
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Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 44, 225-232 (2017-10-03)
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