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127221

Sigma-Aldrich

Di(2-pyridyl) ketone

99%

Synonym(s):

2,2′-Carbonyldipyridine, 2,2′-Dipyridyl ketone

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About This Item

Empirical Formula (Hill Notation):
C11H8N2O
CAS Number:
19437-26-4
Molecular Weight:
184.19
Beilstein:
126598
EC Number:
243-067-3
MDL number:
MFCD00006288
UNSPSC Code:
12352100
PubChem Substance ID:
24847770
NACRES:
NA.22

Quality Level

100

Assay

99%

form

solid

mp

52-55 °C (lit.)

SMILES string

O=C(c1ccccn1)c2ccccn2

InChI

1S/C11H8N2O/c14-11(9-5-1-3-7-12-9)10-6-2-4-8-13-10/h1-8H

InChI key

QPOWUYJWCJRLEE-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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Application

di-2-Pyridyl ketone has been used in the preparation of unusual {Ni(II)(3)Ln(III)(μ-OR)(6)}(3+) complexes with a "star" topology. Its monoanionic form has been used in the synthesis of triangular Ni(2)M (M = lanthanide, Y) complexes.

Biochem/physiol Actions

The Schiff base ligands derived from di-2-pyridyl ketone exhibit antiproliferative activity in SK-N-MC neuroepithelioma (cancer) cells.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Unusual {Ni(II)(3)Ln(III)(μ-OR)(6)}(3+) complexes with a "star" topology have been prepared with ligands derived from the metal-promoted reduction of di-2-pyridyl ketone under solvothermal conditions; the Dy(III) member shows weak single-molecule-magnet behavior.
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