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124214

Sigma-Aldrich

Ethylene glycol butyl ether

99%

Synonym(s):

2-Butoxyethanol, Butyl glycol

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About This Item

Linear Formula:
CH3(CH2)3OCH2CH2OH
CAS Number:
111-76-2
Molecular Weight:
118.17
Beilstein:
1732511
EC Number:
203-905-0
MDL number:
MFCD00002884
UNSPSC Code:
12352104
PubChem Substance ID:
24847605

vapor density

4.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)
10 mmHg ( 81 °C)

Assay

99%

autoignition temp.

473 °F

expl. lim.

10.6 %

availability

not available in USA and Canada

refractive index

n20/D 1.419 (lit.)

bp

169-172.5 °C (lit.)

mp

−75 °C (lit.)

density

0.902 g/mL at 25 °C (lit.)

SMILES string

CCCCOCCO

InChI

1S/C6H14O2/c1-2-3-5-8-6-4-7/h7H,2-6H2,1H3

InChI key

POAOYUHQDCAZBD-UHFFFAOYSA-N

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Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H302,H315,H319,H331

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

152.6 °F - Pensky-Martens closed cup

Flash Point(C)

67 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
U22731
U21366
06910PV
03723EX
00504LP

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Gintautas Korinth et al.
Archives of toxicology, 81(12), 833-840 (2007-06-20)
By regulatory authorities the rat is considered to be a suitable animal model to predict the percutaneous absorption of hazardous substances in humans. In our study, the percutaneous penetration of 2-butoxyethanol (BE) and toluene was compared in different rat models.
Annette L Bunge et al.
International journal of pharmaceutics, 435(1), 50-62 (2012-02-15)
Absorption of 2-butoxyethanol (BE) from neat and aqueous solutions of BE was measured through rat skin in vitro and in vivo and through silicone membranes. Like previous studies in human and guinea pig skin, BE flux increased proportional to BE
Daphna Laifenfeld et al.
Toxicological sciences : an official journal of the Society of Toxicology, 113(1), 254-266 (2009-10-09)
To understand the molecular mechanisms underlying compound-induced hemangiosarcomas in mice, and therefore, their human relevance, a systems biology approach was undertaken using transcriptomics and Causal Network Modeling from mice treated with 2-butoxyethanol (2-BE). 2-BE is a hemolytic agent that induces
Horst Christoph Broding et al.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 9(8), 618-627 (2011-07-28)
Presently, percutaneous absorption of potentially hazardous chemicals in humans can only be assessed in animal experiments, in vitro, or predicted mathematically. Our aim was to demonstrate the proof-of-principle of a novel quantitative in vivo assay for percutaneous absorption: confocal Raman
Tawny Hung et al.
Clinical toxicology (Philadelphia, Pa.), 48(6), 569-571 (2010-06-22)
2-butoxyethanol (2BE) is a solvent commonly incorporated into household and industrial cleaning products. Its ingestion causes rapid central nervous system depression, hypotension, and metabolic acidosis attributable to metabolism of the parent compound to butoxyacetic acid (BAA) by alcohol dehydrogenase. Lactic
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