105538
7-Chloro-4-hydroxyquinoline
99%
Synonym(s):
7-Chloro-4-quinolinol
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About This Item
Empirical Formula (Hill Notation):
C9H6ClNO
CAS Number:
Molecular Weight:
179.60
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Recommended Products
Assay
99%
mp
276-279 °C (lit.)
SMILES string
Oc1ccnc2cc(Cl)ccc12
General description
7-Chloro-4-hydroxyquinoline is formed by the reaction of 4,7-dichloroquinoline with glacial acetic acid in anhydrous medium.
Biochem/physiol Actions
7-Chloro-4-hydroxyquinoline is an antitumor drug.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The reaction of 4, 7-dichloroquinoline with acetic acid.
Cutler RA and Surrey AR.
Journal of the American Chemical Society, 72(8), 3394-3395 (1950)
Antioxidative or prooxidative effect of 4-hydroxyquinoline derivatives on free-radical-initiated hemolysis of erythrocytes is due to its distributive status.
Liu ZQ, et al.
Biochim. Biophys. Acta Gen. Subj., 1570(2), 97-103 (2002)
Chloroquine metabolism in man: urinary excretion of 7-chloro-4-hydroxyquinoline and 7-chloro-4-aminoquinoline metabolites.
N D Brown et al.
Journal of chromatography, 345(1), 209-214 (1985-11-29)
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