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M6514

Sigma-Aldrich

3-(Trimethoxysilyl)propyl methacrylate

≥97%

Synonym(s):

Silane A174, [3-(Methacryloyloxy)propyl]trimethoxysilane

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About This Item

Linear Formula:
H2C=C(CH3)CO2(CH2)3Si(OCH3)3
CAS Number:
2530-85-0
Molecular Weight:
248.35
Beilstein:
1952435
EC Number:
219-785-8
MDL number:
MFCD00008593
UNSPSC Code:
47101511
PubChem Substance ID:
24897091
NACRES:
NA.56

Assay

≥97%

form

liquid

refractive index

n20/D 1.431 (lit.)

bp

190 °C (lit.)

density

1.045 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CO[Si](CCCOC(=O)C(C)=C)(OC)OC

InChI

1S/C10H20O5Si/c1-9(2)10(11)15-7-6-8-16(12-3,13-4)14-5/h1,6-8H2,2-5H3

InChI key

XDLMVUHYZWKMMD-UHFFFAOYSA-N

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General description

3-(Trimethoxysilyl)propyl methacrylate (TMSPMA) is a hydrophobic monomer. The presence of an additional functional group of acrylate facilitates TMSPMA for grafting polymerization on plastic surfaces. 3-(Trimethoxysilyl)propyl methacrylate undergoes first-order kinetic polymerization to form polyTMSPMA, which is a moisture stable polymer.

Application

3-(Trimethoxysilyl)propyl methacrylate has been used in the following applications:
  • Isoelectric focusing can lead to pH gradient formation resulting in the swelling or shrinking of gel casts. This can be prevented by using 3-(Trimethoxysilyl)propyl methacrylate to link polyacrylamide gels to glass plates covalently.
  • In situ hybridization using 3-(Trimethoxysilyl)propyl methacrylate along with poly-L-lysine is a faster and durable method to attach cells, microscopic sections, and total organs to slides/other glass surfaces.
  • 3-(Trimethoxysilyl)propyl methacrylate is also used in the preparation of organic/inorganic hybrid nanomaterials.

Packaging

A product Information sheet is supplied which describes procedures for using this product.

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Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

197.6 °F - closed cup

Flash Point(C)

92 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Aguadé et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(11), 4658-4662 (1994-05-24)
Single-strand conformation polymorphism (SSCP) analysis followed by DNA sequencing of stratified sub-samples was used to survey DNA polymorphism in the su(s) and su(wa) regions in a natural population of Drosophila melanogaster. su(s) and su(wa) are located near the telomere of
Method for attachment of microscopic preparations on glass for in situ hybridization, PRINS and in situ PCR studies.
H M Dyanov et al.
BioTechniques, 18(5), 822-824 (1995-05-01)
Bozhen Zhang et al.
Journal of materials chemistry. B, 9(35), 7196-7204 (2021-07-23)
Label-free cell sorting devices are of great significance for biomedical research and clinical therapeutics. However, current platforms for label-free cell sorting cannot achieve continuity and selectivity simultaneously, resulting in complex steps and limited reliability. Here, an immunoaffinity-based cell catch-transport-release thermo-chemo-mechanical
Improvements of DNA sequencing gels.
H Garoff et al.
Analytical biochemistry, 115(2), 450-457 (1981-08-01)
Preparation of organic/inorganic hybrid nanomaterials using aggregates of poly (stearyl methacrylate)-b-poly (3-(trimethoxysilyl) propyl methacrylate) as precursor.
Junfeng Zhou.
Eur. Polymer J., 5, 1736-1743 (2007)
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