The molecular weight of this product is approximately 240 kDa.
A7003
Alginic acid from brown algae
powder
Synonym(s):
Alginic acid from Macrocystis pyrifera (kelp), Mixed polymer of mannuronic and guluronic acid
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About This Item
Linear Formula:
(C6H8O6)n
CAS Number:
UNSPSC Code:
12171500
EC Number:
232-680-1
NACRES:
NA.47
MDL number:
Pricing and availability is not currently available.
form
powder
Quality Level
technique(s)
titration: suitable
color
white to light yellow
pH range
1.5-3.5
mp
300 °C
solubility
H2O: insoluble, but swells, aqueous base: soluble
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
General description
Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae.[1] It is reported to inhibit the reverse transcriptase activity of HIV.[1] Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported.[2] Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported.[3] Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported. It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).
Application
Alginic acid is suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates.[4] It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.
Other Notes
A straight-chain, hydrophilic, colloidal, polyuronic acid composed primarily of anhydro-β-D-mannuronic acid residues with 1→4 linkage.
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This Item | |||
|---|---|---|---|
| technique(s) titration: suitable | technique(s) - | technique(s) - | technique(s) - |
| color white to light yellow | color white to light beige | color white to brown | color white to brown |
| application(s) diagnostic assay manufacturing | application(s) - | application(s) - | application(s) advanced drug delivery |
| solubility H2O: insoluble, but swells, aqueous base: soluble | solubility - | solubility water: 10 mg/mL, cloudy to hazy, faintly yellow | solubility water: 10 mg/mL, slightly hazy to strongly hazy, faintly yellow to yellow |
| form powder | form powder | form powder | form powder |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Ramón Rial et al.
Nanomaterials (Basel, Switzerland), 10(7) (2020-07-09)
Hydrogels exhibit excellent properties that enable them as nanostructured scaffolds for soft tissue engineering. However, single-component hydrogels have significant limitations due to the low versatility of the single component. To achieve this goal, we have designed and characterized different multi-component
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A7003-1KG | 04061833383193 |
| A7003-500G | 04061833648070 |
| A7003-250G | 04061833648063 |
| A7003-100G | 04061833383186 |
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What is the molecular weight of A7003 alginic acid?
1 answer-
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What is the purity of the product?
1 answer-
The purity of this product is not determined.
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What is the M:G ratio for A7003 alginic acid?
1 answer-
The mannuronic and guluronic content of the alginic acid in product A7003 is not a measured. The information stated on the product datasheet - 61% mannuronic acid and 39% guluronic acid - is on the basis of what is reported in the literature. Please see the link below to review the Product Information Sheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/376/103/a7003pis.pdfHelpful?
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