A3233

L-Arginase from bovine liver

Protein ≥70 % by biuret, powder

• Synonym(s): L-Arginine amidinase, L-Arginine amidino-hydrolase
• CAS Number: 9000-96-8
• UNSPSC Code: 12352204
• NACRES: NA.77
• EC Number: 232-570-3
• MDL number: MFCD00081368
• EC Number: 3.5.3.1 (BRENDA, IUBMB)
• Specific activity: ≥100 units/mg protein
• Biological source: bovine liver

Properties

• biological source: bovine liver
• Quality Segment: 200
• form: powder
• specific activity: ≥100 units/mg protein
• composition: Protein, ≥70% biuret
• UniProt accession no.: Q58DL1
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: cow ... ARG2(518752)

Description

General description

L-arginase is also called as L-arginine amidinohydrolase. It exists in two forms, such as arginase-1 and arginase-2. Arginase-1 is present in liver cells and arginase-2 is seen usually in extrahepatic tissues like, kidney, brain, skeletal muscle, small intestine and the lactating mammary gland. Arginase -2 is mapped to human chromosome 14q24.1−24.3.

Biochem/physiol Actions

L-arginase hydrolyze L-arginine into L-ornithine and urea, which is the last step of the urea cycle in the liver of ureotelic species. Arginase plays a major role in the mammalian immune system and the enzyme participates in several aspects of inflammation.

L-Arginase is the major degradative enzyme for arginine; converts arginine to ornithine.

L-Arginase is the major degradative enzyme for arginine; converts arginine to ornithine; deficiency is associated with spasticity and motor dysfunction.

Other Notes

One unit will cause the hydrolysis of 1.0 μmole of L-arginine per minute at pH 9.5 and 37 °C.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H334
• pcodes: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)