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Merck

09341

8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt

suitable for fluorescence, BioReagent, ≥96.0% (HPCE)

Synonym(s):

1,3,6-Pyrenetrisulfonic acid, 8-amino trisodium salt, APTS, Trisodium 8-aminopyrene-1,3,6-trisulfonate

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About This Item

Empirical Formula (Hill Notation):
C16H8NNa3O9S3
CAS Number:
Molecular Weight:
523.40
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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product line

BioReagent

Quality Segment

assay

≥96.0% (HPCE)

mp

≥250 °C (lit.)

solubility

DMF: soluble, DMSO: soluble, H2O: soluble

fluorescence

λex 420 nm; λem 500 nm in 0.1 M Tris pH 7.4 (quenching with Vitamin B1), λex 488 nm; λem 520 nm(lit.)

suitability

suitable for fluorescence

SMILES string

[Na+].[Na+].[Na+].Nc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H11NO9S3.3Na/c17-11-5-12(27(18,19)20)8-3-4-10-14(29(24,25)26)6-13(28(21,22)23)9-2-1-7(11)15(8)16(9)10;;;/h1-6H,17H2,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3

InChI key

XSTNYACEWLNWPY-UHFFFAOYSA-K

Application

Fluorescent label for saccharides and glycoproteins.
APTS is a fluorescence reagent that has been demonstrated to have a high level of detection sensitivity for sugars The LOD for APTS-derivatized sugars has been shown to be 0.4 nM when using a 488 nm argon-ion laser. The multi-anionic nature of APTS makes it ideal for the studies of carbohydrate molecules and small hormone molecules by high resolution capillary electrophoresis.
Fluorescent label for glycoproteins and saccharides.

Other Notes

Fluorescent probe for derivatising sugars


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pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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R.A. Evangelista et al.
Analytical Chemistry, 67, 2239-2239 (1995)
M Meininger et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1012-1013, 193-203 (2016-02-07)
Recombinant human erythropoietin (rhEPO) is an important CHO cell-derived glycoprotein and the degree of sialylation of this hormone is crucial for its in vivo bioactivity. In order to improve the purification process serotonin as a potential affinity ligand was tested
René Hennig et al.
Biochimica et biophysica acta, 1860(8), 1728-1738 (2016-04-04)
Facilitated by substantial advances in analytical methods, plasma N-glycans have emerged as potential candidates for biomarkers. In the recent years, several investigations could link aberrant plasma N-glycosylation to numerous diseases. However, due to often limited specificity and sensitivity, only a



Global Trade Item Number

SKUGTIN
E14705-25G04061837329906
E14705-5G04061837329913
09341-5MG04061838656179
09341-25MG04061838656148