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Sigma-Aldrich

Celpure® P1000

meets USP/NF testing specifications

Synonym(s):

Diatomaceous earth, flux-calcined, Filter agent

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About This Item

CAS Number:
68855-54-9
MDL number:
MFCD00132803
UNSPSC Code:
11101527
PubChem Substance ID:
329757848
NACRES:
NA.21

Agency

meets USP/NF testing specifications

Quality Level

200

form

powder

specific activity

≤1 EU/g (endotoxin)

composition

SiO2, 98%

parameter

1.000 (Permeability(Darcy))

impurities

≤0.2% water solubles
≤2.0% acid solubles
≤4 ppm EtOH/citric acid solubles
≤50 mg non-siliceous content

particle size

1.0-2.0 mm

cation traces

As: ≤10 ppm (leachable)
Fe: ≤5 ppm (acid soluble)
Pb: ≤10 ppm (leachable)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Celpure® P1000 (Diatomaceous earth, DE) is natural amorphous silica formed from the fossilized skeletons of diatoms. It is extracted, crushed, dried and calcined with or without flux material. DE is widely used as filler in construction materials, paints and as anti-caking agent for agricultural chemicals. It has high water and oil absorption ability. The potential toxicity of different samples of DE has been assessed. DE is also employed as an adsorbent for column chromatography.

Application

For high-purity, high-throughput processes

Legal Information

Product of Imerys Filtration Minerals
Celpure is a registered trademark of Advanced Minerals Corporation

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The global variability of diatomaceous earth toxicity: a physicochemical and in vitro investigation.
Nattrass C, et al.
Journal of Occupational Medicine and Toxicology (London, England), 10(1), 25-25 (2015)
H Checkoway et al.
British journal of industrial medicine, 50(7), 586-597 (1993-07-01)
A cohort mortality study was conducted among workers from two plants in the diatomaceous earth mining and processing industry in California. Diatomaceous earth consists of the skeletal remains of diatoms. Exposure to amorphous (non-crystalline) and crystalline silica in the form
Induction of p53-independent growth inhibition in lung carcinoma cell A549 by gypenosides.
Journal of cellular and molecular medicine (2015).
Liu JS, et al.
Journal of Cellular and Molecular Medicine, 19(7), 1697-1709 (2015)
Manipulating surface wettability and oil absorbency of diatomite depending on processing and ambient conditions.
Ozen I, et al.
Applied Surface Science, 332, 22-31 (2015)
Junhua Li et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 917-918, 30-35 (2013-01-29)
A basic polypeptide L2 (252-273) derived from Escherichia coli ribosomal protein L2 was used as a purification tag. In order to develop faster, less expensive methods for expression and purification of proteins, the L2 (252-273)-small ubiquitin like modifier (SUMO) fusion
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