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Z2251

Sigma-Aldrich

Zinquin ethyl ester

≥95% purity (HPLC), solid

Synonym(s):

2-Methyl-8-[(4-methylphenyl)sulfonylamino]-6-(ethyloxycarbonylmethyloxy)quinoline

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About This Item

Empirical Formula (Hill Notation):
C21H22N2O5S
Molecular Weight:
414.47
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Zinquin ethyl ester, ≥95% (HPLC), solid

Assay

≥95% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble
methanol: soluble

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c3nc(C)ccc3c1

InChI

1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3

InChI key

KCASTCXJTDRDFT-UHFFFAOYSA-N

Biochem/physiol Actions

Used to detect zinc in cells by UV fluorescence.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sarah R Aldhaheri et al.
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In light of the recent lead contamination of the water in Flint, Michigan and its potential adverse outcomes, much research and media attention has turned towards the safety profile of commonly used chelators. Dimercapto-1-propanesulfonic acid (DMPS) typically used in the
Correlation of apoptosis with change in intracellular labile Zn(ll) using
Zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid],
a new specific fluorescent probe for Zn(ll)
Peter D
The Biochemical Journal (1993)
Xianqiang Li et al.
Toxicology mechanisms and methods, 28(7), 520-528 (2018-04-27)
It is recently shown that biological macromolecules in food could interact with nanoparticles (NPs) and consequently change the biological effects of NPs. In this study, the interactions between ZnO NPs with or without hydrophobic surface coating and bovine serum albumin
Phuong Kim To et al.
International journal of molecular sciences, 19(10) (2018-10-10)
The prostate gland contains a high level of intracellular zinc, which is dramatically diminished during prostate cancer (PCa) development. Owing to the unclear role of zinc in this process, therapeutic applications using zinc are limited. This study aimed to clarify
Travis J Bourret et al.
Molecular microbiology, 81(1), 259-273 (2011-05-14)
Borrelia burgdorferi encounters potentially harmful reactive nitrogen species (RNS) throughout its infective cycle. In this study, diethylamine NONOate (DEA/NO) was used to characterize the lethal effects of RNS on B. burgdorferi. RNS produce a variety of DNA lesions in a

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