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δ-Tocotrienol

analytical standard

Synonym(s):

(R)-δ-Tocotrienol, 8-Methyltocotrienol, [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol

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About This Item

Empirical Formula (Hill Notation):
C27H40O2
CAS Number:
Molecular Weight:
396.61
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

biological source

Elaeis guineensis

Quality Level

grade

analytical standard

Assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

colorless to amber

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

−20°C

SMILES string

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC[C@]1(C)CCc2cc(O)cc(C)c2O1

InChI

1S/C27H40O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1

InChI key

ODADKLYLWWCHNB-LDYBVBFYSA-N

Related Categories

General description

δ-Tocotrienol can be found in coconut oil, palm oil, and cereal grains such as barley, oats, wheat and rye.
δ-Tocotrienol is known as one of the homologs of Vitamin E.

Application

δ-Tocotrienol may be used as an analytical reference standard for the determination of δ-tocotrienol in:
  • Food samples of vegetable origin by high performance liquid chromatography-fluorescene detection (HPLC-FLD).
  • Chicken meat samples by LC-FLD.
  • Cereals by normal phase HPLC-FLD.
  • Rice bran samples by one-step equilibrium extraction method coupled to reversed-phase HPLC combined with dual wavelength ultraviolet-visible (UV-Vis) detector.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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A rapid procedure for analysing rice bran tocopherol, tocotrienol and gamma-oryzanol contents.
Chen MH and Bergman CJ
J. Food Compos. Anal., 18(2-3), 139-151 (2005)
Jing-Shu Zhang et al.
Toxicology, 285(1-2), 8-17 (2011-04-02)
Tocotrienol is considered a beneficial effect agent on inhibition of tumor development. In this study, we focused on the effects of δ-tocotrienol and its possible mechanism on induction of death in human colon cancer SW620 cells. δ-Tocotrienol inhibited proliferation of
Xiangming Ji et al.
Anticancer research, 32(7), 2647-2655 (2012-07-04)
Non-small cell lung cancer (NSCLC), accounting for 80% of lung cancers, is the leading cause of all cancer deaths. Previously, we demonstrated that delta-tocotrienol inhibits NSCLC cell proliferation, invasion and induces apoptosis by down-regulation of the Notch-1 signaling pathway. The
Xiangming Ji et al.
Journal of cellular biochemistry, 112(10), 2773-2783 (2011-05-21)
Lung cancer is the leading cause of death among all cancers. Non-small cell lung cancer accounts for 80% of lung cancer with a 5-year survival rate of 16%. Notch pathway, especially Notch-1 is up-regulated in a subgroup of non-small cell
Determination of carotene, tocopherols and tocotrienols in residue oil from palm pressed fiber using pressurized liquid extraction-normal phase liquid chromatography
Sanagi MM, et al.
Analytica Chimica Acta, 538(1-2), 71-76 (2005)

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