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Key Documents

QBD10787

Sigma-Aldrich

Biotin-dPEG®23-azide

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C58H112N6O25S
Molecular Weight:
1325.60
UNSPSC Code:
12352125
PubChem Substance ID:
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: Biotinylations
reagent type: cross-linking reagent

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Features and Benefits

Biotin-dPEG®23-azide is a single molecular weight dPEG® that permits biotin labeling with precise spacing to molecules containing an alkyne using well-known, highly popular click chemistry. By inserting an alkyne function into the target molecule, site specific labeling can occur using either copper(I) catalyzed or strain-catalyzed click chemistry. The single molecular weight nature of the dPEG® spacer (87.7 Å) allows the user to precisely tailor the distance between the biotin and the target molecule in order to receive optimal binding between biotin and avidin.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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