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Sigma-Aldrich

Ethylenediamine diacetate

98%

Synonym(s):

Ethanediammonium diacetate

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About This Item

Linear Formula:
NH2CH2CH2NH2 · 2CH3COOH
CAS Number:
38734-69-9
Molecular Weight:
180.20
Beilstein:
5444394
MDL number:
MFCD00192147
UNSPSC Code:
12352100
PubChem Substance ID:
24866331
NACRES:
NA.22

Assay

98%

mp

118-120 °C (lit.)

SMILES string

CC(O)=O.CC(O)=O.NCCN

InChI

1S/C2H8N2.2C2H4O2/c3-1-2-4;2*1-2(3)4/h1-4H2;2*1H3,(H,3,4)

InChI key

SAXQBSJDTDGBHS-UHFFFAOYSA-N

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Application

  • Catalytic Synthesis: Utilization of Ethylenediamine Diacetate as an effective catalyst for synthesizing specific thioxothiazolidin-4-one, important for organic chemists and pharmacological studies aiming at new drug development (S Holota, A Lozynskyi, Y Konechnyi, Y Shepeta, 2021).
  • Reaction of New Amides: Exploration of reactions between new N-(2,2-Dichloro-1-cyanoethenyl)amides and aliphatic amines facilitated by Ethylenediamine Diacetate, relevant for medicinal chemistry and synthesis (OV Shablykin, SA Chumachenko, 2021).
  • Microwave-Assisted Organic Synthesis: Application of Ethylenediamine Diacetate in microwave-assisted synthesis processes, which is valuable for accelerating chemical reactions in drug synthesis and material processing (P Martín-Acosta, G Feresin, A Tapia, 2016).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Ethylenediamine diacetate (EDDA)-catalyzed one-pot synthesis of tetrahydroquinolines by domino Knoevenagel/hetero Diels-Alder reactions from 1, 3-dicarbonyls.
Lee YR and Hung TV.
Tetrahedron, 67(49), 9627-9634 (2011)
Efficient and general method for the synthesis of benzopyrans by ethylenediamine diacetate-catalyzed reactions of resorcinols with α, β-unsaturated aldehydes. One step synthesis of biologically active (?)-confluentin and (?)-daurichromenic acid.
Lee YR, et al.
Tetrahedron Letters, 46(44), 7539-7543 (2005)
Euan Pyle et al.
Cell chemical biology, 25(7), 840-848 (2018-04-24)
The role of membrane lipids in modulating eukaryotic transporter assembly and function remains unclear. We investigated the effect of membrane lipids in the structure and transport activity of the purine transporter UapA from Aspergillus nidulans. We found that UapA exists
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International journal of radiation biology, 96(4), 502-509 (2019-12-13)
Purpose: Early and accurate imaging of glioblastoma is of great value in staging, metastatic detection, treatment management and prognosis. The human epidermal growth factor receptor 2 (HER2) plays an essential role in the tumorigenesis and tumor progression in cancer. The
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Journal of labelled compounds & radiopharmaceuticals, 60(9), 431-438 (2017-05-26)
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