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Principaux documents

1440808

USP

Metoclopramide hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide monohydrochloride monohydrate, Metoclopramide monohydrochloride monohydrate

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About This Item

Formule empirique (notation de Hill):
C14H22ClN3O2 · HCl · H2O
Numéro CAS:
54143-57-6
Poids moléculaire :
354.27
Numéro MDL:
MFCD00150634
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

metoclopramide

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

[Cl-].Clc1c(cc(c(c1)C(=O)NCCN(CC)CC)OC)N.O.[H+]

InChI

1S/C14H22ClN3O2.ClH.H2O/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H;1H2

Clé InChI

KJBLQGHJOCAOJP-UHFFFAOYSA-N

Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metoclopramide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Metoclopramide Tablets
  • Metoclopramide Oral Solution
  • Metoclopramide Injection
  • Prazosin Hydrochloride

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

M1824990

Metoclopramide, European Pharmacopoeia (EP) Reference Standard

M1825010

N,N-Diéthyléthylènediamine, European Pharmacopoeia (EP) Reference Standard

M1825000

Metoclopramide hydrochloride, European Pharmacopoeia (EP) Reference Standard

M1824995

Metoclopramide impurity A, European Pharmacopoeia (EP) Reference Standard

1440820

Metoclopramide Related Compound B, United States Pharmacopeia (USP) Reference Standard

1440841

Metoclopramide Related Compound D, United States Pharmacopeia (USP) Reference Standard

1440819

Metoclopramide Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP357

Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2283

Metoclopramide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2284

Metoclopramide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2285

Metoclopramide Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2286

Metoclopramide Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2287

Methyl 4-(Acetylamino)-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2506

Metoclopramide Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2507

Metoclopramide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2508

Methyl 4-Amino-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Radwa A Mohamed et al.
The Journal of pharmacy and pharmacology, 65(11), 1607-1621 (2013-10-10)
The purpose of this study was to formulate and characterize metoclopramide solid lipid nanoparticles (MCP-SLNs) and incorporating it into suppository bases for treatment of nausea and vomiting, produced with chemotherapeutic agents, using one dose per day. MCP-SLNs was prepared using
Ray M Merrill et al.
BMC psychiatry, 13, 152-152 (2013-05-30)
To identify the incidence rate of spontaneous dyskinesia (SD) and tardive dyskinesia (TD) in a general population and to examine the association between dykinesia and potential risk factors (exposure to metoclopramide [MCP], antipsychotic drugs, and history of diabetes and psychoses).
Z Eras et al.
European review for medical and pharmacological sciences, 17(12), 1655-1657 (2013-07-09)
Gastroesophageal reflux disease (GERD) may occur with poor weight gain, esophagitis, hematemesis and respiratory problems in an infant. Common treatment strategies include positioning, feeding thickeness, histamine2 receptor antagonists, antiacids, and prokinetics. Metoclopramide is a prokinetic drug used to treat GERD
Moshe Yair Kasirer et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(5), G439-G444 (2014-01-11)
Feeding intolerance resulting from delayed gastric emptying is common in premature neonates. Metoclopramide (MCP), the most frequently used prokinetic drug in neonates, enhances gastric muscle contractility through inhibition of dopamine receptors. Although its therapeutic benefit is established in adults, limited
Allen Lee
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 17(9), 1553-1556 (2013-06-27)
Gastroparesis is a chronic motility disorder that leads to delayed gastric emptying and negatively impacts morbidity, mortality, and quality of life. This paper provides an overview of the pathophysiology leading to symptoms in gastroparesis, discusses tests for diagnosis, and examines
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