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UC448

Sigma-Aldrich

Paracetamol sulfate potassium salt

solid, ≥97% (HPLC)

Synonyme(s) :

Acetaminophen sulfate phosphate salt

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About This Item

Formule empirique (notation de Hill):
C8H8KNO5S
Numéro CAS:
32113-41-0
Poids moléculaire :
269.32
Numéro MDL:
MFCD01631667
Code UNSPSC :
12161501
ID de substance PubChem :
329827671
Nomenclature NACRES :
NA.77

Pureté

≥97% (HPLC)

Forme

solid

Couleur

white to off-white

Pf

163 °C

Solubilité

H2O: soluble

Température de stockage

2-8°C

Chaîne SMILES 

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1

Clé InChI

AJYPYWFCUWHZMZ-UHFFFAOYSA-M

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Description générale

Paracetamol is an aminophenol derivative. It functions as an analgesic and antipyretic drug, which has weak inflammatory effect. Paracetamol is used to treat pyrexia and mild to moderate pain. It might inhibit atherosclerosis through its antioxidant activity.

Application

Paracetamol sulfate potassium salt has been used as a standard for HPLC assays of acetaminophen.

Actions biochimiques/physiologiques

Phase II metabolite of paracetamol.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Notes préparatoires

Paracetamol sulfate potassium salt is soluble in water.

Autres remarques

Occasionally, it may be necessary to supply as the sodium salt

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H315,H317,H318,H335

Classification des risques

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Hayati Filik et al.
Chemical & pharmaceutical bulletin, 54(6), 891-896 (2006-06-07)
In the present paper, conventional spectrophotometry in conjunction with cloud point extraction-preconcentration were investigated as alternative methods for paracetamol (PCT) assay in urine samples. Cloud point extraction (CPE) was employed for the preconcentration of p-aminophenol (PAP) prior to spectrophotometric determination
D Bougie et al.
Blood, 97(12), 3846-3850 (2001-06-05)
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in
Paracetamol: past, present, and future.
Prescott LF
American Journal of Therapeutics, 7(2), 143-147 (2000)
Karel Allegaert et al.
Acta paediatrica (Oslo, Norway : 1992), 94(9), 1273-1279 (2005-11-11)
Major changes in drug clearance and metabolism are observed during infancy, in part based on ontogenic regulation of various metabolic pathways. Since paracetamol provides a good substrate to study UGT (1A6) activity, urinary metabolites of propacetamol were determined in neonates
A K Hewavitharana et al.
Analytical biochemistry, 374(1), 106-111 (2007-12-18)
An HPLC-MS/MS method has been developed for the selective quantitative analysis of paracetamol and its two major metabolites. The use of tandem MS enabled the detection and quantitation of metabolites in small sample sizes with high sensitivity and selectivity. Isocratic
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