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SML3990

Sigma-Aldrich

BODIPY FL-NHS ester

new

≥98% (HPLC)

Synonyme(s) :

(T-4)-[1-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN]-1-oxopropoxy]-2,5-pyrrolidinedionato]difluoroboron, BDP FL NHS ester, BDP FL SE, BODIPY FL NHS, Bodipy FL succinimidyl ester

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About This Item

Formule empirique (notation de Hill):
C18H18BF2N3O4
Numéro CAS:
146616-66-2
Poids moléculaire :
389.16
Code UNSPSC :
12352107
Code UNSPSC :
12352200

Niveau de qualité

100

Pureté

≥98% (HPLC)

Forme

powder

Couleur

, Light orange to very dark red

Solubilité

DMSO: 2 mg/mL, clear

Température de stockage

-10 to -25°C

Chaîne SMILES 

O=C(CCC1=CC=C2C=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]21)[F-])ON4C(CCC4=O)=O

Actions biochimiques/physiologiques

Amine reactive green fluorescent dye that can be used to label molecules like antibodies, proteins, peptides, and nucleic acids.



BODIPY FL-NHS ester is a versatile amine sensitive fluorescent labeling reagent that can be used to tag antibodies, proteins, peptides, and nucleic acids. BODIPY (boron-dipyrromethene) dyes are known for their excellent photophysical properties, including high fluorescence quantum yield, good photostability, and wide spectral tunability. BODIPY FL has a distinctive absorption peak (excitation) at 503-505 nm and an emission peak at 512-514 nm, resulting in bright green fluorescence. BODIPY FL is used in a wide range of applications, including immunofluorescence, live cell imaging, FRET experiments, and other fluorescence-based studies.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Shengrong Pei et al.
Bioconjugate chemistry, 34(12), 2194-2204 (2023-09-25)
α6β4* nicotinic acetylcholine receptor (nAChR) (* represents the possible presence of additional subunits) is mainly distributed in the central and peripheral nervous system and is associated with neurological diseases, such as neuropathic pain; however, the ability to explore its function
Jun Yang et al.
The Journal of pharmacology and experimental therapeutics, 321(2), 462-468 (2007-02-10)
Despite the widely accepted assumption that most endosomal compartments are acidic, evaluation of the efficiency of pH-dependent drug release from a ligand-targeted drug conjugate during receptor-mediated endocytosis is lacking. Therefore, we have characterized the kinetics of pH-dependent drug release from
Jenna M Franke et al.
Journal of the American Chemical Society, 141(32), 12824-12831 (2019-07-25)
Fluorophores based on the BODIPY scaffold are prized for their tunable excitation and emission profiles, mild syntheses, and biological compatibility. Improving the water-solubility of BODIPY dyes remains an outstanding challenge. The development of water-soluble BODIPY dyes usually involves direct modification

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