SML2261

Conivaptan hydrochloride

≥98% (HPLC)

• Synonyme(s) : N-[4-[(4,5-dihydro-2­methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]- [1,1’-biphenyl]-2-carboxamide monohydrochloride
• Formule empirique (notation de Hill) : C₃₂H₂₆N₄O₂ · HCl
• Numéro CAS: 168626-94-6
• Poids moléculaire : 535.04
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00945712
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propriétés

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(NC1=CC=C(C(N2CCC(N=C(C)N3)=C3C4=C2C=CC=C4)=O)C=C1)C5=CC=CC=C5C6=CC=CC=C6.Cl
• InChI: 1S/C32H26N4O2.ClH/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22;/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37);1H
• InChI key: BTYHAFSDANBVMJ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Conivaptan hydrochloride is a novel dual Arginine vasopressin receptor (AVP-R) antagonist for AVP-R types 1a (V1a) and V2-R. Conivaptan potently inhibits AVP-induced intracellular signaling through human V2 and V1a receptors with no agonistic activity.

Nonpeptide, dual vasopressin V1a/V2 receptor antagonist

Informations sur la sécurité

• Pictogrammes: GHS08
• Mot-clé: Warning
• Codes de danger: H361fd
• Mentions de précaution: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable