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PVP1

Sigma-Aldrich

Poly(vinylpyrrolidone)–Iodine complex

Synonyme(s) :

PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne® antiseptic

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About This Item

Numéro CAS:
25655-41-8
Numéro MDL:
MFCD00084483
Code UNSPSC :
51102829
ID de substance PubChem :
24899316
Nomenclature NACRES :
NA.85

Forme

powder

Niveau de qualité

200

Solubilité

H2O: 100 mg/mL

Spectre d'activité de l'antibiotique

Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
viruses
yeast

Mode d’action

protein synthesis | interferes

Chaîne SMILES 

II.C=CN1CCCC1=O

InChI

1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;

Clé InChI

CPKVUHPKYQGHMW-UHFFFAOYSA-N

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Catégories apparentées

Application

Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.

Actions biochimiques/physiologiques

PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.

Autres remarques

An iodophor; "tamed iodine."
Keep container tightly closed in a dry and well-ventilated place.

Informations légales

Povadyne is a registered trademark of National Patent Development Corp.

Pictogrammes

CorrosionEnvironment
GHS05,GHS09

Mention d'avertissement

Danger

Mentions de danger

H315,H318,H411

Classification des risques

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

>212.0 °F - Not applicable

Point d'éclair (°C)

> 100 °C - Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Yangzi Jiang et al.
Acta biomaterialia, 9(9), 8089-8098 (2013-05-28)
Polyvinylpyrrolidone-iodine (Povidone-iodine, PVP-I) is widely used as an antiseptic agent for lavation during joint surgery; however, the biological effects of PVP-I on cells from joint tissue are unknown. This study examined the biocompatibility and biological effects of PVP-I on cells
X X Hao et al.
Poultry science, 92(10), 2560-2566 (2013-09-21)
Lots of microorganisms exist in layer houses can cause bird diseases and worker health concerns. Spraying chemical disinfectants is an effective way to decontaminate pathogenic microorganisms in the air and on surfaces in poultry houses. Slightly acidic electrolyzed water (SAEW
A Tuna et al.
Australian dental journal, 57(4), 435-439 (2012-11-29)
The aim of this pilot study was to evaluate the effects of mouthrinses containing 7.5% povidone iodine and 0.2% chlorhexidine on bacteraemia following impacted third molar surgery. Thirty-four patients were enrolled in this study. Patients in the first group were
Philippe Seguin et al.
Critical care medicine, 42(1), 1-8 (2013-10-10)
To evaluate the efficacy and safety of oral care with povidone-iodine on the occurrence of ventilator-associated pneumonia in a high-risk population. A multicenter, placebo-controlled, randomized, double-blind, two-parallel-group trial performed between May 2008 and May 2011. Six ICUs in France. One
E Pels et al.
The British journal of ophthalmology, 83(9), 1019-1026 (1999-08-26)
Povidone-iodine (PVP -I) is applied for microbial decontamination of human eyes donated for transplantation. Concentrations and immersion times vary greatly. The effectiveness and toxicity of PVP-I were assessed for different decontamination protocols. Human donor eyes and corneas were immersed in
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