M149

Methiothepin mesylate salt

≥98% (HPLC), solid

• Synonyme(s) : 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt, Metitepine mesylate salt
• Formule linéaire : C₂₀H₂₄N₂S₂ · CH₃SO₃H
• Numéro CAS: 74611-28-2
• Poids moléculaire : 452.65
• NACRES: NA.77
• PubChem Substance ID: 24278104
• UNSPSC Code: 12352200
• MDL number: MFCD00153831
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Propriétés

• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white
• solubility: H₂O: 13 mg/mL
• SMILES string: CS(O)(=O)=O.CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1
• InChI: 1S/C20H24N2S2.CH4O3S/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20;1-5(2,3)4/h3-8,14,18H,9-13H2,1-2H3;1H3,(H,2,3,4)
• InChI key: CZMDZGZYKOGLJY-UHFFFAOYSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR6(3362), HTR7(3363)

Description

General description

Methiothepin belongs to a new class of dibenzothiophenes. Methiothepin possesses neuroleptic activity.

Application

Methiothepin mesylate salt has been used to explore the relationship between circulating cells and the niche. It has also been used in serotonin (5-HT) and antagonists in vivo bioassays and in in vivo antagonist and lipopolysaccharide stimulations.

Biochem/physiol Actions

Methiothepin mesylate salt is a 5-HT₁, 5-HT₆, 5-HT₇ serotonin receptor antagonist, which blocks serotonin autoreceptors.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)