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E6758

Ethylenediaminetetraacetic acid

Name: Ethylenediaminetetraacetic acid
Brand: SIGMA

anhydrous, crystalline, BioReagent, suitable for cell culture

Synonyme(s) :

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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A propos de cet article

Formule linéaire :

(HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂

Numéro CAS:

60-00-4

Poids moléculaire :

292.24

NACRES:

NA.25

PubChem Substance ID:

24894634

eCl@ss:

39030907

UNSPSC Code:

12161700

EC Number:

200-449-4

MDL number:

MFCD00003541

Beilstein/REAXYS Number:

1716295

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Propriétés

grade

anhydrous

product line

BioReagent

assay

≥98.5%

form

crystalline

reaction suitability

reagent type: chelator

technique(s)

cell culture | mammalian: suitable

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

solubility

3 M NaOH: 100 mg/mL

density

1.46 g/cm³ at 20 °C

cation traces

C: 40.7-41.5%, N: 9.3-9.8%

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

Description

Application

Ethylenediaminetetraacetic acid has been used:

as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
as a medium component in the hepatic stellate cell (HSCs) culture
as a component of homogenization buffer for protein extraction from eye tissues
for stopping benzonase reaction in lysis buffer

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

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Warning

Classe de stockage

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

target_organs

Respiratory Tract

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation

wgk

WGK 3

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Lot/Batch Number

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