E6005

Ethionamide

≥98.0%, suitable for ligand binding assays

• Synonyme(s) : 2-Ethyl-4-pyridinecarbothioamide
• Formule empirique (notation de Hill) : C₈H₁₀N₂S
• Numéro CAS: 536-33-4
• Poids moléculaire : 166.24
• NACRES: NA.26
• PubChem Substance ID: 24894350
• UNSPSC Code: 12352111
• EC Number: 208-628-9
• MDL number: MFCD00057361

Propriétés

• Nom du produit: Ethionamide,
• assay: ≥98.0%
• Quality Segment: 200
• form: powder
• technique(s): ligand binding assay: suitable
• color: yellow
• storage temp.: 2-8°C
• SMILES string: CCc1cc(ccn1)C(N)=S
• InChI: 1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)
• InChI key: AEOCXXJPGCBFJA-UHFFFAOYSA-N

Description

General description

Ethionamide (ETA, ETH), a thioamide, is an anti-tuberculosis agent used as a second-line therapy in treating tuberculosis when other agents are not effective. The structure of ETA is similar to isoniazid.

Application

Ethionamide is used in antimicrobials and in potency assay of test compounds on M. tuberculosis.

Biochem/physiol Actions

Ethionamide is used as an anti-tuberculosis antibiotic and an inducer of hypothyroidism.

Informations sur la sécurité

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges